[Ring-13C6]-Diclofenac

[Ring-13C6]-Diclofenac is a labeled form of diclofenac, a non-steroidal anti-inflammatory drug (NSAID) that is commonly used for the treatment of pain and inflammation. This labeled form of diclofenac is created by replacing six carbon atoms in the aromatic ring of the diclofenac molecule with their heavier isotope, carbon-13. This allows for the tracking and identification of the drug in biological systems. The usage of [Ring-13C6]-Diclofenac is mainly in pharmacokinetic studies, where it is used to understand the absorption, distribution, metabolism, and excretion of the drug in humans and animals. The labeled drug is administered to the subject and its presence and concentration in various biological fluids, such as blood and urine, are measured over time. This information can then be used to determine the drug's bioavailability, clearance, and half-life. Chemical information about [Ring-13C6]-Diclofenac includes its molecular formula as C14H8Cl2N2O2^13C6, its molecular weight as 326.19 g/mol, and its CAS number as 1243021-49-2. The labeled drug has the same chemical properties and mechanism of action as diclofenac, which inhibits the production of prostaglandins, thus reducing inflammation and pain. However, it is important to note that the labeled drug may have slightly different pharmacokinetic properties compared to the unlabeled drug, which should be taken into consideration when interpreting study results.