Etoricoxib 13C6

[13C6]-Etoricoxib is a labeled version of the nonsteroidal anti-inflammatory drug (NSAID) etoricoxib, which is used to treat pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. The label in [13C6]-Etoricoxib refers to the addition of six carbon-13 isotopes to the molecular structure of etoricoxib, which allows for more precise tracking and analysis of the drug's metabolism and pharmacokinetics in the body. As an NSAID, etoricoxib works by inhibiting the activity of cyclooxygenase-2 (COX-2), an enzyme that plays a key role in the production of prostaglandins, which are involved in the inflammatory response. By reducing the production of prostaglandins, etoricoxib can help to alleviate pain and inflammation. In terms of chemical information, [13C6]-Etoricoxib has a molecular formula of C18H15C6NO2S and a molecular weight of 396.52 g/mol. The addition of the carbon-13 isotopes does not significantly alter the chemical properties or pharmacological activity of etoricoxib, but does allow for more precise analysis of its pharmacokinetics and metabolism in the body. Overall, [13C6]-Etoricoxib is a useful tool for researchers and clinicians seeking to better understand the pharmacological activity and metabolic fate of etoricoxib in the body, and may have applications in drug development, clinical trials, and personalized medicine.