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[13C4]-All-trans-retinal is a stable isotope-labeled version of all-trans-retinal, which is a derivative of vitamin A and a key component of the visual pigments in the retina of the eye. The stable isotope labeling of [13C4]-All-trans-retinal allows for its use as a tracer molecule in various biological and chemical studies, including metabolic pathways and protein-protein interactions.
All-trans-retinal is formed when light hits the retina, causing the conversion of the light-sensitive pigment rhodopsin into its activated form, metarhodopsin II. Metarhodopsin II then catalyzes the conversion of all-trans-retinal from vitamin A to its active form, which triggers a cascade of events that ultimately result in the perception of light. The use of [13C4]-All-trans-retinal as a tracer in these studies can provide valuable insights into the mechanisms of vision and the underlying chemical processes.
In addition to its role in vision, all-trans-retinal has been shown to have antioxidant and anti-inflammatory properties, and may have potential therapeutic applications in the treatment of neurodegenerative diseases and cancer. The use of stable isotope-labeled [13C4]-All-trans-retinal in these studies can help to elucidate the mechanisms of action of all-trans-retinal and its potential therapeutic benefits.
Overall, [13C4]-All-trans-retinal is a valuable tool for researchers studying various biological and chemical processes, and its stable isotope labeling provides a unique opportunity to gain insights into the mechanisms of vision and other biological processes.
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