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[13C5]-Didanosine

Chemical Name [13C5]-Didanosine
CAT No. CS-EK-00384
CAS Registry# 503173-93-1
Status Under Certification (Usually dispatched in 5 days)
Category Stable Isotopes
Hazardous This is not a Hazardous Compound
COA View Sample COA
Controlled No

Additional Information


Controlled No
Parent API Didanosine
Hazardous No


Usage and description


[13C5]-Didanosine is a stable isotope-labeled form of Didanosine, an antiretroviral drug used for the treatment of HIV/AIDS. It is used in medical research studies and clinical trials that aim to investigate the pharmacokinetics and metabolism of Didanosine in the human body. Chemically, [13C5]-Didanosine is a purine nucleoside analog that inhibits the reverse transcriptase enzyme. It is structurally similar to the natural nucleosides found in human DNA and RNA, but it differs in the sugar moiety, which is replaced by a modified form of ribose. This modification enhances the drug’s potency and selectivity against the HIV virus, making it an effective treatment option for HIV/AIDS patients. The stable isotopes of carbon in [13C5]-Didanosine are used in carbon-13 nuclear magnetic resonance (NMR) spectroscopy, a powerful analytical technique that allows researchers to study the molecular structure, dynamics, and interactions of the drug in the body. By using [13C5]-Didanosine in NMR experiments, scientists can obtain precise information on the drug’s metabolic fate, bioavailability, and pharmacokinetics, which can help in the development of more efficient and safer antiretroviral therapies. In conclusion, [13C5]-Didanosine is a valuable tool for medical research and drug development studies that require accurate and detailed information on the pharmacological properties of Didanosine. Its stable isotope labeling provides a unique chemical signature that can be used to track the drug’s behavior in vivo, facilitating the design of more effective and targeted therapies for HIV/AIDS patients.

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