[13C6]-Phenacetin

[13C6]-Phenacetin is a stable isotope-labeled version of the commonly used pain reliever Phenacetin. This compound is used in pharmacokinetic studies to determine the absorption, distribution, metabolism, and excretion of the drug in the body. The stable isotope labeling allows for precise measurement and quantification of the drug and its metabolites in biological samples. Phenacetin was initially used as a pain reliever, but its use has been discontinued due to its association with kidney damage and cancer. However, [13C6]-Phenacetin is still widely used in research studies as a reference compound in drug metabolism and pharmacokinetic studies. The chemical structure of [13C6]-Phenacetin is similar to Phenacetin, with the addition of six carbon-13 isotopes. The molecular formula of [13C6]-Phenacetin is C₁₃H₈D₆NO₂, and its molecular weight is 216.25 g/mol. The compound is a white crystalline powder that is slightly soluble in water and highly soluble in organic solvents. In summary, [13C6]-Phenacetin is a stable isotope-labeled version of Phenacetin that is used in pharmacokinetic studies to determine the drug's absorption, distribution, metabolism, and excretion in the body. Its chemical structure is similar to Phenacetin, with the addition of six carbon-13 isotopes, and it is a white crystalline powder that is slightly soluble in water and highly soluble in organic solvents.