Product Name |
[13C6]-Etravirine |
Alternate Names |
Etravirine Stable Isotopes, Stable Isotopes of Etravirine |
CAT No. |
CS-EK-00455
|
CAS No. |
1261392-42-0 |
Category |
Stable Isotopes |
Stock |
Enquire
|
Mol. Wt. |
Not Available |
Mol. For. |
Not Available
|
Hazardous |
This is not a Hazardous Compound
|
COA |
View Sample COA
|
MSDS |
View Sample MSDS
|
Parent API |
Etravirine |
Controlled |
No |
Shipping |
Free for purchase above 1000$ |
Delivery |
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Return |
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Ordering |
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[13C6]-Etravirine is a stable isotope-labeled version of the anti-retroviral drug Etravirine. Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 in combination with other antiretroviral drugs. NNRTIs work by binding to the reverse transcriptase enzyme, which is essential for the replication of the virus, and inhibiting its activity. This prevents the virus from multiplying and reduces the amount of HIV in the bloodstream.
[13C6]-Etravirine is used in pharmacokinetic studies to measure the absorption, distribution, metabolism, and excretion of Etravirine in the body. By adding stable isotopes to the drug molecule, researchers can track the drug's movement in the body and determine how it is metabolized and eliminated. This information is important for optimizing dosing regimens and predicting potential drug-drug interactions.
In terms of chemical information, [13C6]-Etravirine has a molecular weight of 435.52 g/mol and a chemical formula of C23H18N3O2S. The stable isotope labeling involves replacing six carbon atoms in the drug molecule with the stable isotope carbon-13. This does not affect the drug's mechanism of action but allows for more precise measurement in pharmacokinetic studies.
Overall, [13C6]-Etravirine is a valuable tool in understanding the pharmacokinetics of Etravirine and improving the treatment of HIV-1.