Acemetacin 13C6
| Product Name | Acemetacin 13C6 |
|---|---|
| Alternate Names | Acemetacin Stable Isotopes, Stable Isotopes of Acemetacin |
| CAT No. | CS-EK-00483 |
| CAS No. | 53164-05-9 unlabeled |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Acemetacin |
| Canonical Smiles | CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)OCC(=O)O |
| InchIKey | FSQKKOOTNAMONP-UHFFFAOYSA-N |
| Inchl | InChI=1S/C21H18ClNO6/c1-12-16(10-20(26)29-11-19(24)25)17-9-15(28-2)7-8-18(17)23(12)21(27)13-3-5-14(22)6-4-13/h3-9H,10-11H2,1-2H3,(H,24,25) |
| IUPAC | 2-[2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl]oxyacetic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
[13C6]-Acemetacin is a stable isotope-labeled form of the nonsteroidal anti-inflammatory drug, acemetacin. It is used in various research studies to investigate the pharmacokinetics, metabolism, and pharmacodynamics of the parent drug.
Acemetacin is a prodrug that is metabolized to indometacin, a potent inhibitor of cyclooxygenase (COX) enzymes that are responsible for the synthesis of prostaglandins. By suppressing the activity of COX enzymes, acemetacin and its active metabolite indometacin can reduce pain, inflammation, and fever.
[13C6]-Acemetacin contains six stable carbon-13 isotopes, which can be detected and quantified using advanced analytical techniques such as mass spectrometry. This labeling allows for the precise measurement of the pharmacokinetics and metabolic fate of acemetacin in the body.
The chemical structure of [13C6]-Acemetacin is identical to that of the unlabeled parent drug, consisting of a benzene ring, a carboxylic acid group, and a methyl ester group. The incorporation of stable isotopes does not affect the biological activity or pharmacological properties of the drug, making it a valuable tool in drug development and clinical research.
In summary, [13C6]-Acemetacin is a useful tool in investigating the pharmacokinetics and metabolism of acemetacin, a nonsteroidal anti-inflammatory drug that is commonly used to manage pain, inflammation, and fever. Its stable isotope labeling allows for precise measurement and analysis of the drug's behavior in the body.
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Related Compounds
Acemetacin D4 |