Isotretinoin 13C3

Product Name Isotretinoin 13C3
Alternate Names Isotretinoin Stable Isotopes, Stable Isotopes of Isotretinoin
CAT No. CS-EK-00854
CAS No. 4759-48-2 unlabeled
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Isotretinoin
Canonical Smiles CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
InchIKey SHGAZHPCJJPHSC-XFYACQKRSA-N
Inchl InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14-
IUPAC (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
Controlled No
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[13C3]-Isotretinoin is a synthetic retinoid used in the treatment of severe acne. It is a derivative of vitamin A and works by reducing the amount of oil produced by the skin's sebaceous glands. The isotopic labeling of three carbon atoms with the stable isotope 13C allows for accurate pharmacokinetic studies of the drug in vivo. The chemical formula of [13C3]-Isotretinoin is C20H27[13C3]O2 and its molecular weight is 327.5 g/mol. It is a yellow to orange crystalline powder that is insoluble in water but soluble in organic solvents. The recommended dose of [13C3]-Isotretinoin varies depending on the severity of the acne and the patient's weight. It is typically taken orally once or twice a day with food for 15-20 weeks. Common side effects include dry skin, chapped lips, and increased sensitivity to sunlight. In rare cases, it can cause more serious side effects such as depression, liver damage, and birth defects if taken during pregnancy. [13C3]-Isotretinoin is metabolized by the liver and excreted primarily in the urine. Studies have shown that it has a half-life of approximately 21 hours in humans. Overall, [13C3]-Isotretinoin is a valuable tool for studying the pharmacokinetics and metabolism of isotretinoin in vivo and has proven to be an effective treatment option for severe acne.

Related Compounds

Isotretinoin D5 |

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