Trospium chloride 13C6

[13C6]-Trospium chloride is a medication that is primarily used to treat overactive bladder symptoms such as frequent urination, urgency, and incontinence. It works by blocking the acetylcholine receptors in the bladder, which reduces the involuntary contractions of the bladder muscle and thus increases the capacity of the bladder to hold urine. [13C6]-Trospium chloride contains six carbon atoms that are labeled with the stable isotope carbon-13, which allows for the tracking and identification of the compound in biological systems using mass spectrometry. The compound is a quaternary ammonium salt with a molecular weight of 427.03 g/mol. The pharmacokinetics of [13C6]-Trospium chloride have been extensively studied, and it has been found to be rapidly absorbed after oral administration, with a maximum plasma concentration reached within 2-3 hours. The compound is highly protein-bound and is metabolized in the liver by hydrolysis and conjugation reactions, with the majority of the metabolites being excreted in the urine. Overall, [13C6]-Trospium chloride is a well-tolerated and effective medication for the treatment of overactive bladder symptoms, with a low risk of adverse effects and drug interactions. Its unique labeling with the carbon-13 isotope makes it a valuable tool for pharmacokinetic studies and drug metabolism research.