[3-13C]-L-Glutamine

[3-13C]-L-Glutamine is a stable isotope-labeled amino acid that is often used in metabolic studies. It is a modified form of L-glutamine, which is an essential amino acid that plays an important role in protein synthesis, energy production, and other metabolic processes in the body. The stable isotope labeling of [3-13C]-L-Glutamine allows researchers to track the fate of this amino acid in metabolic pathways, providing valuable insights into cellular metabolism. In terms of chemical information, [3-13C]-L-Glutamine is a white crystalline powder that is soluble in water. It has a molecular weight of 148.1 g/mol and a chemical formula of C5H10N2O3. The stable isotope labeling involves the substitution of three carbon atoms with the heavier isotope, carbon-13. This labeling allows researchers to distinguish between the labeled and unlabeled forms of glutamine in metabolic studies. [3-13C]-L-Glutamine is commonly used in studies of cancer metabolism, as cancer cells have unique metabolic pathways that differ from normal cells. It has also been used in studies of neurological disorders, such as Alzheimer's disease, where disturbances in glutamine metabolism have been observed. Overall, the use of [3-13C]-L-Glutamine in metabolic studies provides a powerful tool for investigating the complex metabolic processes that occur in living organisms.