Product Name |
6-alpha-Hydroxypaclitaxel 13C6 |
Alternate Names |
Paclitaxel Stable Isotopes, Stable Isotopes of Paclitaxel |
CAT No. |
CS-EK-01124
|
CAS No. |
153212-75-0 unlabeled |
Category |
Stable Isotopes |
Stock |
Enquire
|
Mol. Wt. |
Not Available |
Mol. For. |
Not Available
|
Hazardous |
This is not a Hazardous Compound
|
COA |
View Sample COA
|
MSDS |
View Sample MSDS
|
Parent API |
Paclitaxel |
Controlled |
No |
Shipping |
Free for purchase above 1000$ |
Delivery |
In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
Return |
Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
Ordering |
Place your order online or by email sales@clearsynth.com |
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[13C6]-6-alpha-Hydroxypaclitaxel is a chemically modified version of the anti-cancer drug paclitaxel that is labeled with carbon-13 isotopes. Paclitaxel is widely used in the treatment of various types of cancer, including breast, ovarian and lung cancer. However, the effectiveness of paclitaxel is limited by its poor solubility, toxicity and drug resistance. The modification of paclitaxel with carbon-13 isotopes allows for its easy detection and quantification in biological samples, which is useful for pharmacokinetic studies.
[13C6]-6-alpha-Hydroxypaclitaxel is synthesized by introducing six carbon-13 isotopes into the paclitaxel molecule at specific positions. This modification does not affect the anti-cancer activity of paclitaxel, but it does alter the drug's properties. The presence of carbon-13 isotopes alters the drug's mass, making it easy to detect in biological samples through techniques such as mass spectrometry. This allows for accurate measurement of drug levels in the blood, tissues and urine, which helps in determining the optimal dosage and dosing schedule for paclitaxel.
In summary, [13C6]-6-alpha-Hydroxypaclitaxel is a chemically modified version of the anti-cancer drug paclitaxel that is labeled with carbon-13 isotopes. This modification allows for easy detection and quantification of the drug in biological samples, which is useful for pharmacokinetic studies.