[13C6]-O-Didesmethylerlotinib hydrochloride

[13C6]-O-Didesmethylerlotinib hydrochloride is a labeled compound that is used in research studies to explore the pharmacokinetics and pharmacodynamics of erlotinib, a tyrosine kinase inhibitor that is used in the treatment of non-small-cell lung cancer. This labeled compound contains six carbon-13 isotopes, which allows researchers to track its movement through the body and determine its metabolic fate. Erlotinib works by inhibiting the activity of the epidermal growth factor receptor (EGFR), which is overexpressed in many types of cancer. By blocking this receptor, erlotinib can slow or stop the growth of cancer cells. [13C6]-O-Didesmethylerlotinib hydrochloride is used to study the absorption, distribution, metabolism, and excretion of erlotinib in animal models and in vitro systems. It can also be used to investigate the potential for drug-drug interactions or to determine the optimal dosing regimen for erlotinib in patients. The chemical formula for [13C6]-O-Didesmethylerlotinib hydrochloride is C22H19ClN4O3, and its molecular weight is 426.86 g/mol. It is a white to off-white powder that is soluble in water and organic solvents. The compound is stable under normal laboratory conditions and should be stored in a cool, dry place away from light and moisture.