Tamoxifen 13C6

[13C6]-Tamoxifen is a labeled version of the breast cancer drug tamoxifen. It is used in research studies to track the metabolism and distribution of tamoxifen in biological systems. The stable carbon-13 isotopes in [13C6]-Tamoxifen allow for accurate and sensitive detection by mass spectrometry, enabling researchers to monitor the drug and its metabolites in various tissues and organs. Tamoxifen is a selective estrogen receptor modulator (SERM) that is commonly used for the treatment of hormone receptor-positive breast cancer. It works by binding to estrogen receptors in breast tissue, blocking the effects of estrogen and preventing the growth of cancer cells. Tamoxifen is also used for breast cancer prevention in women at high risk for the disease. Chemically, [13C6]-Tamoxifen is a derivative of tamoxifen that has six carbon atoms replaced with carbon-13 atoms, which are stable isotopes. This labeling allows for precise detection and quantification of tamoxifen and its metabolites in biological samples. The chemical structure of [13C6]-Tamoxifen is similar to that of tamoxifen, with a triphenylethylene core and a side chain containing a dimethylamino group. In summary, [13C6]-Tamoxifen is a valuable tool for research studies focused on understanding the pharmacokinetics and metabolism of tamoxifen in biological systems. Its stable isotope labeling allows for sensitive detection and accurate quantification of tamoxifen and its metabolites, providing important insights into the drug's mechanism of action and potential side effects.