[U-13C6]-Thiotepa

[U-13C6]-Thiotepa is a radiolabeled derivative of Thiotepa, a cancer chemotherapy agent that is used to treat various types of cancer. The radiolabeled compound is used in research to study the pharmacokinetics, metabolism, and efficacy of Thiotepa in cancer treatment. The U-13C6 labeling of the compound refers to the substitution of six carbon atoms in the molecule with the stable isotope carbon-13, which allows for the tracking of the compound in biological systems using mass spectrometry. Thiotepa works by damaging the DNA of cancer cells, which leads to their death. The compound is primarily used to treat breast, ovarian, bladder, and lung cancers. [U-13C6]-Thiotepa is used in research to study the metabolism of the drug in vivo and in vitro. It is particularly useful in studying the pharmacokinetics of the drug because the radiolabeled compound can be tracked using imaging techniques such as positron emission tomography (PET). In terms of chemical information, [U-13C6]-Thiotepa has a molecular weight of 294.4 g/mol and a chemical formula of C10H16N3PSC6H613C6. The compound is a white to off-white crystalline powder that is soluble in water and ethanol. It is important to note that [U-13C6]-Thiotepa is a hazardous substance and should be handled with care. Overall, [U-13C6]-Thiotepa is a valuable tool in cancer research that allows for the study of the pharmacokinetics and metabolism of Thiotepa in biological systems.