[13C6]-Canagliflozin

[13C6]-Canagliflozin is a stable isotope-labelled version of the drug Canagliflozin, which is primarily used for the treatment of type 2 diabetes. Canagliflozin is a selective inhibitor of the sodium-glucose cotransporter 2 (SGLT2) and works by reducing the absorption of glucose from the kidneys. This leads to a decrease in excess glucose levels in the bloodstream, which ultimately helps to regulate blood sugar levels in diabetic patients. The addition of the stable isotope carbon-13 (13C6) to Canagliflozin allows researchers to use advanced analytical techniques, such as mass spectrometry, to track the drug's metabolism within the body. This information can be used to better understand the pharmacokinetics and pharmacodynamics of Canagliflozin and to develop more effective treatment strategies. Chemically, [13C6]-Canagliflozin is a white to off-white powder that is soluble in water and methanol. Its molecular formula is C24H25ClO13S2 and its molecular weight is 635.07 g/mol. The stable isotope-labelled drug is typically administered orally and is available in tablet form. Overall, [13C6]-Canagliflozin is an important tool for diabetes research and drug development. Its unique chemical properties allow researchers to gain a better understanding of how the drug works in the body and to develop more effective treatments for type 2 diabetes.