Chlorthalidone 13C6

[13C6]-Chlorthalidone is a labeled version of the medication Chlorthalidone, which is a diuretic medication used to treat high blood pressure and fluid retention. The labeling of [13C6]-Chlorthalidone refers to the substitution of six carbon atoms with the stable isotope carbon-13, which allows for the tracking and identification of the medication in biological systems using analytical techniques such as mass spectrometry. Chlorthalidone works by increasing the excretion of sodium and water from the body, which helps to reduce the volume of blood and lower blood pressure. It is often used in combination with other medications to achieve optimal blood pressure control. [13C6]-Chlorthalidone can be used in clinical studies to investigate the pharmacokinetics and metabolism of Chlorthalidone in the body, as well as to monitor compliance and assess drug interactions. In terms of chemical information, Chlorthalidone has a molecular weight of 338.77 g/mol and a chemical formula of C14H11ClN2O4S. The labeling of [13C6]-Chlorthalidone results in a molecular weight of 344.83 g/mol. It is a white crystalline powder that is slightly soluble in water and has a melting point of 263-269°C. The medication is primarily metabolized by the liver and excreted in the urine. Common side effects of Chlorthalidone include dizziness, headache, and increased urination.