[1,2-13C2,15N]-L-Proline

[1,2-13C2,15N]-L-Proline is a stable isotope-labeled compound that is commonly used in metabolic and proteomic studies. It is a modified form of the amino acid proline, where the carbon atoms at positions one and two are replaced with ^13C isotopes, and the nitrogen atom at position 15 is replaced with a ^15N isotope. This modification allows for the tracking and identification of the labeled proline using mass spectrometry. The labeled proline is commonly used in studies involving protein turnover, where it can be used to measure the rate of protein synthesis and degradation. It is also used in studies of collagen biosynthesis, where proline is a critical component of collagen molecules. The labeled proline can be incorporated into newly synthesized collagen molecules, allowing for the measurement of collagen turnover rates. In addition to its usage in metabolic and proteomic studies, [1,2-13C2,15N]-L-Proline has also been used in studies of brain metabolism and neurotransmitter synthesis. The labeled proline can be used to measure the rate of neurotransmitter synthesis and turnover, providing insight into the function of the nervous system. Overall, [1,2-13C2,15N]-L-Proline is a valuable tool in a wide range of scientific studies, providing important insights into protein and metabolic processes. Its stable isotope labeling allows for precise measurements and tracking of labeled molecules, making it an essential component of many research projects.