[2-13C]-L-Proline

[2-13C]-L-Proline is a stable isotope-labeled amino acid that is commonly used in biochemical research and medical applications. It is a modified form of the amino acid proline, which contains two carbon atoms labeled with the stable isotope carbon-13. This labeling allows for the tracking and analysis of the metabolic pathways and biochemical processes in which proline is involved. One of the primary uses of [2-13C]-L-Proline is in studies of collagen synthesis and turnover. Collagen is a major component of connective tissue and is essential for maintaining the strength and elasticity of skin, bones, and other tissues. Proline is an important building block of collagen, and the labeled amino acid can be used to track the incorporation of proline into newly synthesized collagen molecules. This information can be used to study the effects of various diseases and treatments on collagen metabolism. In addition to its use in collagen research, [2-13C]-L-Proline has also been used in studies of protein folding and stability, as well as in metabolic studies of cancer cells. Its stable isotope labeling makes it a useful tool for tracking the metabolism of proline and its role in various physiological processes. Overall, [2-13C]-L-Proline is a valuable tool for researchers studying a variety of biochemical and physiological processes, and its stable isotope labeling provides important insights into the metabolic pathways and functions of proline in the body.