Ketoprofen 13C6

[13C6]-Ketoprofen is a stable isotope-labeled form of the nonsteroidal anti-inflammatory drug Ketoprofen. It is primarily used in pharmacokinetic studies to understand the drug's metabolic pathways and its effects on the body. By labeling six carbon atoms in the Ketoprofen molecule with 13C, researchers can trace the drug's fate in the body through various analytical techniques such as mass spectrometry and nuclear magnetic resonance spectroscopy. Chemically, [13C6]-Ketoprofen has a molecular formula of C16H13NaO3 with a molecular weight of 284.26 g/mol. It has a melting point of 94-97°C and is soluble in water, ethanol, and dimethyl sulfoxide. It is typically administered orally or intravenously in small doses for pharmacokinetic studies in humans and animals. [13C6]-Ketoprofen is a potent inhibitor of cyclooxygenase enzymes, which are responsible for the synthesis of prostaglandins that cause inflammation and pain. It works by inhibiting the production of these enzymes, thus reducing the levels of prostaglandins in the body. Its pharmaceutical applications include the treatment of various inflammatory conditions such as rheumatoid arthritis, osteoarthritis, and acute pain. Overall, [13C6]-Ketoprofen is a valuable tool for researchers studying the pharmacokinetics and pharmacodynamics of Ketoprofen, which can help in the development of more effective and safer anti-inflammatory drugs.