6-Mercaptopurine 13C3, 15N2

[13C3, 15N2]-6-Mercaptopurine is a modified version of the drug 6-mercaptopurine, which is a purine analog that inhibits the synthesis of DNA and RNA. The modification involves the substitution of three carbon atoms and two nitrogen atoms with isotopes of carbon and nitrogen, respectively. This modification is useful in certain types of research, such as metabolic labeling and protein quantification studies. In terms of usage, [13C3, 15N2]-6-Mercaptopurine can be used in metabolic labeling studies to track the fate of the drug within the body. The isotopic substitution allows for the drug to be distinguished from the endogenous form of the drug, as well as other compounds that may be present in the sample. This can provide valuable information on the pharmacokinetics and metabolism of the drug. Chemically, [13C3, 15N2]-6-Mercaptopurine has a molecular formula of C7H4N4S and a molecular weight of 198.23 g/mol. The isotopic substitution results in a slight shift in the mass spectrum, allowing for easy identification and quantification. The drug is typically administered orally, with a half-life of approximately 1.5 hours in humans. It is primarily metabolized by the liver and excreted in the urine. Overall, [13C3, 15N2]-6-Mercaptopurine is a useful tool in research for studying the metabolism and pharmacokinetics of the drug. Its isotopic substitution allows for easy identification and quantification, making it a valuable tool in metabolic labeling studies.