Captopril 13C5,15N

[13C5,15N]-Captopril is a labeled form of captopril, which is an angiotensin-converting enzyme (ACE) inhibitor used to treat hypertension and heart failure. This labeled form of captopril contains five carbon-13 (13C) atoms and one nitrogen-15 (15N) atom, which can be used for research purposes such as drug metabolism studies, pharmacokinetics, and drug-drug interactions. The chemical formula of [13C5,15N]-Captopril is C13H16N2O3S, and its molecular weight is 300.4 g/mol. The compound works by inhibiting ACE, which is an enzyme that converts angiotensin I to angiotensin II, a potent vasoconstrictor that increases blood pressure. By blocking this enzyme, captopril helps to relax blood vessels and lower blood pressure. The labeled form of captopril can be used in various research methods such as nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry, and positron emission tomography (PET) imaging. It can also be used in drug-drug interaction studies to determine how a specific drug may affect the metabolism and clearance of captopril. Overall, [13C5,15N]-Captopril is a valuable tool in drug research and can provide important information on drug metabolism, pharmacokinetics, and drug-drug interactions.