[13C6]-Vemurafenib
| Product Name | [13C6]-Vemurafenib |
|---|---|
| CAT No. | CS-EK-02644 |
| CAS No. | 918504-65-1 unlabeled |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Canonical Smiles | CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=C2C=C(C=N3)C4=CC=C(C=C4)Cl)F |
| InchIKey | GPXBXXGIAQBQNI-UHFFFAOYSA-N |
| Inchl | InChI=1S/C23H18ClF2N3O3S/c1-2-9-33(31,32)29-19-8-7-18(25)20(21(19)26)22(30)17-12-28-23-16(17)10-14(11-27-23)13-3-5-15(24)6-4-13/h3-8,10-12,29H,2,9H2,1H3,(H,27,28) |
| IUPAC | N-[3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]propane-1-sulfonamide |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
[13C6]-Vemurafenib is a stable isotope-labeled version of the anti-cancer drug vemurafenib. The stable isotope labeling is done by replacing some of the carbon atoms in the molecule with the stable carbon-13 isotope. This labeling is done to aid in the analysis and characterization of the drug in biological systems.
Vemurafenib is a drug used in the treatment of patients with BRAF V600E mutation-positive metastatic melanoma. It works by inhibiting the activity of the BRAF protein, which is overactive in these cancer cells. The stable isotope-labeled version of vemurafenib, [13C6]-Vemurafenib, can be used to track the drug in biological systems using techniques such as mass spectrometry. This can aid in understanding the pharmacokinetics and metabolism of the drug in vivo.
Chemically, [13C6]-Vemurafenib is a white to off-white powder with a molecular weight of 510.6 g/mol. It has a melting point of 210-212°C and is soluble in DMSO and ethanol. The drug has a half-life of around 57 hours in humans and is predominantly metabolized by the liver. The stable isotope labeling of the drug does not affect its efficacy or safety when used in patients.
In conclusion, [13C6]-Vemurafenib is a stable isotope-labeled version of the anti-cancer drug vemurafenib. It is used to aid in the analysis and characterization of the drug in biological systems. The drug works by inhibiting the activity of the BRAF protein and has a half-life of around 57 hours in humans.
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