(S)-Luliconazole-E-Isomer

Product Name (S)-Luliconazole-E-Isomer
Alternate Names Luliconazole Impurities, Impurities of Luliconazole
CAT No. CS-EO-00219
CAS No. 256424-63-2
Category Impurities
Stock IN-Stock
Mol. Wt. 354.28 g/mol
Mol. For. C14H9Cl2N3S2
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Luliconazole
Smileys ClC1=C([C@@H](CS/2)SC2=C(N3C=CN=C3)/C#N)C=CC(Cl)=C1
Canonical Smiles C1C(SC(=C(C#N)N2C=CN=C2)S1)C3=C(C=C(C=C3)Cl)Cl
InchIKey YTAOBBFIOAEMLL-MNWMYKRDSA-N
Inchl InChI=1S/C14H9Cl2N3S2/c15-9-1-2-10(11(16)5-9)13-7-20-14(21-13)12(6-17)19-4-3-18-8-19/h1-5,8,13H,7H2/b14-12+/t13-/m1/s1
IUPAC (2E)-2-[(4S)-4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-ylacetonitrile
Controlled No
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(S)-Luliconazole-E-Isomer is a topical antifungal agent used for the treatment of various skin infections caused by fungi. It belongs to the class of azole antifungal agents and is structurally related to imidazoles. The chemical formula of (S)-Luliconazole-E-Isomer is C14H12Cl2N2O and its molecular weight is 298.16 g/mol. It is a chiral molecule with a single stereocenter, and the (S)-enantiomer is the active form of the drug. The mechanism of action of (S)-Luliconazole-E-Isomer involves inhibition of the biosynthesis of ergosterol, a key component of fungal cell membranes. This leads to disruption of the membrane structure and ultimately kills the fungi. The drug has a broad spectrum of activity against various fungal species, including dermatophytes, yeasts, and molds. (S)-Luliconazole-E-Isomer is available as a cream or lotion for topical application. It is typically applied once daily to the affected skin area and rubbed in gently. The duration of treatment varies depending on the type and severity of the infection, but is generally 2-4 weeks. (S)-Luliconazole-E-Isomer is generally well tolerated, with mild and transient side effects such as itching, burning, or redness at the application site. It is contraindicated in patients with hypersensitivity to the drug or any of its components. Overall, (S)-Luliconazole-E-Isomer is a safe and effective option for the treatment of fungal skin infections.

Related Compounds

Luliconazole amide impurity | Rac-Luliconazole-E-Isomer | Racemic Luliconazole | Rac-Luliconazole-Z-Isomer |

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