Axitinib Impurity 8

Chemical Name Axitinib Impurity 8
Alternate Names Axitinib Impurities, Impurities of Axitinib
CAT No. CS-P-07104
CAS Registry# 944835-85-2
Category Impurities
Stock IN-Stock
Mol. Wt. 283.35 g/mol
Mol. For. C₁₅H₁₃N₃OS
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Axitinib
Therapeutic Anti-Cancer / Oncology
Smileys CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C=NN3
Canonical Smiles CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C=NN3
InchIKey JBFLDDCNCFRBIG-UHFFFAOYSA-N
Inchl InChI=1S/C15H13N3OS/c1-16-15(19)12-4-2-3-5-14(12)20-11-7-6-10-9-17-18-13(10)8-11/h2-9H,1H3,(H,16,19)(H,17,18)
IUPAC 2-(1H-indazol-6-ylsulfanyl)-N-methylbenzamide
Controlled No
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Axitinib Impurity 8 is a chemical compound that is commonly used in the pharmaceutical industry as a reference standard during the development and manufacturing of Axitinib drug products. Axitinib is an anti-cancer medication that works by inhibiting the growth and spread of cancer cells in the body. Axitinib Impurity 8 is used as a reference standard to ensure the purity and quality of Axitinib drug products. Chemically, Axitinib Impurity 8 is known as (S)-2-((E)-2-(pyridin-2-yl)ethenyl)-3-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)pyrrolidine. It is a yellow colored powder that is sparingly soluble in water and soluble in organic solvents like methanol, ethanol, and acetonitrile. The chemical structure of Axitinib Impurity 8 is closely related to that of Axitinib, and it is considered an impurity because it is not the desired active ingredient in the drug product. However, it is important to ensure that the level of this impurity in Axitinib drug products is within the acceptable limits set by regulatory agencies. In conclusion, Axitinib Impurity 8 is an important reference standard used in the pharmaceutical industry to ensure the quality and purity of Axitinib drug products. Its chemical properties and structure make it a useful tool for drug development and manufacturing.

Related Compounds

Axitinib Sulfonyl Impurity | Dehydro Axitinib | Axitinib EP Impurity D | Axitinib Impurity 2 | Axitinib N-Formyl impurity | Axitinib Z-isomer | Axitinib Impurity 6 | Axitinib N-Oxide | Axitinib Impurity 9 | Axitinib Impurity 4 | Axitinib Dimer | N-Nitroso Axitinib | Axitinib Dimer (Asymmetric Impurity) | Axitinib Des Iodo analog | Axitinib Impurity 8 | Axitinib adduct -1 | Axitinib Impurity 27 |

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