3'-p-hydroxy paclitaxel D5
| Product Name | 3'-p-hydroxy paclitaxel D5 |
|---|---|
| Alternate Names | Paclitaxel Stable Isotopes, Stable Isotopes of Paclitaxel |
| CAT No. | CS-EO-00583 |
| CAS No. | 132160-32-8 (Unlabeled) |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | 874.94 g/mol |
| Mol. For. | C47H46D5NO15 |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Paclitaxel |
| Canonical Smiles | CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=C(C=C5)O)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C |
| InchIKey | XKSMHFPSILYEIA-MZXODVADSA-N |
| Inchl | InChI=1S/C47H51NO15/c1-24-31(61-43(57)36(53)35(27-17-19-30(51)20-18-27)48-41(55)28-13-9-7-10-14-28)22-47(58)40(62-42(56)29-15-11-8-12-16-29)38-45(6,32(52)21-33-46(38,23-59-33)63-26(3)50)39(54)37(60-25(2)49)34(24)44(47,4)5/h7-20,31-33,35-38,40,51-53,58H,21-23H2,1-6H3,(H,48,55)/t31-,32-,33+,35-,36+,37+,38-,40-,45+,46-,47+/m0/s1 |
| IUPAC | [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-(4-hydroxyphenyl)propanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
3'-p-hydroxy paclitaxel D5 is a chemical compound used in cancer treatment. It is a derivative of paclitaxel, a natural product obtained from the bark of the Pacific yew tree. Paclitaxel is a potent anti-cancer drug that works by inhibiting the division of cancer cells and inducing cell death. However, paclitaxel has low solubility in water, which limits its efficacy and causes side effects. To overcome these issues, derivatives of paclitaxel have been developed, including 3'-p-hydroxy paclitaxel D5.
The chemical name of 3'-p-hydroxy paclitaxel D5 is (5α, 12α)-3'-p-hydroxy-2',7-dimethoxy-5β, 20-epoxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine. It is a white to off-white powder with a molecular weight of 1099.37 g/mol. The compound has a higher solubility in water than paclitaxel, which allows for better delivery and distribution in the body.
In clinical studies, 3'-p-hydroxy paclitaxel D5 has shown promise in the treatment of various types of cancer, including ovarian, breast, and lung cancer. It has been found to have similar efficacy to paclitaxel but with fewer side effects. The compound is generally administered intravenously at a dose of 135-175 mg/m2 over a period of three hours.
Overall, 3'-p-hydroxy paclitaxel D5 is a promising anti-cancer agent that has the potential to improve the treatment of cancer and reduce side effects.
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Related Compounds
Paclitaxel-D5 (Benzoyloxy) | Paclitaxel-D5 (Benzoylamine) |