Vonoprazan Impurity 6

Vonoprazan Impurity 6, also known as 4-[[[4-(4-cyano-3-methylphenyl)-5-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl]methyl]amino]benzonitrile, is a chemical compound that is commonly used in pharmaceutical research and development. It is classified as an impurity of Vonoprazan, which is a proton pump inhibitor used to treat acid-related disorders such as gastroesophageal reflux disease, peptic ulcers, and Zollinger-Ellison syndrome. The chemical structure of Vonoprazan Impurity 6 consists of a triazole ring, a benzene ring, and a nitrile group, among others. It is a white to off-white solid with a molecular weight of 545.6 g/mol. The compound is soluble in organic solvents such as methanol, ethanol, and dimethyl sulfoxide. In terms of usage, Vonoprazan Impurity 6 is primarily used as a reference standard for the analysis of Vonoprazan and its related compounds. It is also used in the synthesis and development of new proton pump inhibitors. The impurity can be synthesized through various methods, including condensation reactions between appropriate starting materials. In conclusion, Vonoprazan Impurity 6 is an important compound in pharmaceutical research and development. Its usage as a reference standard and in the synthesis of new drugs highlights its significance in the field of medicinal chemistry. Its chemical structure and properties provide valuable insights into the development of new proton pump inhibitors and related drugs.