4-Hydroxy Methyl Rac-Ambrisentan D3

4-Hydroxy Methyl Ambrisentan D3 is a deuterated derivative of the selective endothelin receptor antagonist Ambrisentan. It is an essential chemical compound that is used in the research and development of pharmaceuticals that are used in the treatment of pulmonary arterial hypertension (PAH). PAH is a medical condition characterized by high blood pressure in the lungs, which can lead to heart failure and other complications. The compound has a molecular formula of C23H19D3N2O3, and its molecular weight is 373.46 g/mol. It is a white to off-white powder that is soluble in dimethyl sulfoxide and ethanol. 4-Hydroxy Methyl Ambrisentan D3 works by blocking the action of endothelin, a hormone that constricts blood vessels and raises blood pressure. By inhibiting endothelin, 4-Hydroxy Methyl Ambrisentan D3 helps to relax the blood vessels in the lungs, reducing the workload on the heart and improving blood flow. The compound is commonly used in preclinical studies to evaluate its efficacy and safety in the treatment of PAH. It is also used as a reference standard in scientific research and development. The compound must be handled with care due to its potency and potential toxicity. Proper safety measures and protocols must be strictly followed when handling or using this chemical compound. Overall, 4-Hydroxy Methyl Ambrisentan D3 is an essential tool in the development of new therapies for the treatment of PAH.