N-Nitroso Duloxetine D5

N-Nitroso Duloxetine D5 is a chemical compound that belongs to the class of nitrosamines. It is a deuterated analogue of duloxetine, which is an antidepressant drug used to treat major depressive disorder, anxiety disorder, and chronic pain. N-Nitroso Duloxetine D5 is used in research as a stable isotope-labeled internal standard for the quantification of duloxetine in biological matrices. Chemically, N-Nitroso Duloxetine D5 is a yellowish-orange solid with a molecular weight of 322.39 g/mol. It has a melting point of 147-151 °C and a boiling point of 480.1 °C at 760 mmHg. The compound is soluble in organic solvents like methanol, ethanol, and dichloromethane but is sparingly soluble in water. While nitrosamines are known to be carcinogenic, the risk associated with N-Nitroso Duloxetine D5 is considered low due to its stable isotopic labeling. However, the compound should be handled with care and stored in a cool, dry, and well-ventilated area. In conclusion, N-Nitroso Duloxetine D5 is a valuable tool for researchers studying duloxetine metabolism and pharmacokinetics. Its stable isotopic labeling allows for accurate quantification, while its low carcinogenic risk makes it a safe option for laboratory use.