(R)-5-((7-chloro-1H-indol-3-yl)methyl)-3-methyl-D3-imidazolidine-2,4-dione

(R)-5-((7-chloro-1H-indol-3-yl)methyl)-3-methyl-D3-imidazolidine-2,4-dione is a chemical compound that is used in pharmaceutical research as a potential treatment for cancer and other diseases. This compound is a derivative of thalidomide, which was initially developed as a sedative but was later found to have immunomodulatory and anti-inflammatory properties. Thalidomide has been used to treat various conditions, including multiple myeloma and leprosy, but its use has been limited due to its teratogenic effects. The (R)-5-((7-chloro-1H-indol-3-yl)methyl)-3-methyl-D3-imidazolidine-2,4-dione compound is a more potent and selective derivative of thalidomide that has shown promise in preclinical studies for the treatment of cancer. It works by inhibiting angiogenesis, which is the process of new blood vessel formation that is necessary for tumor growth. Additionally, it has been shown to enhance the immune response against cancer cells. Chemically, this compound is a chiral molecule, meaning it exists in two mirror-image forms. The (R)-enantiomer is the active form, while the (S)-enantiomer is inactive. The compound has a molecular weight of 371.8 g/mol and a melting point of 250-252°C. Its chemical formula is C18H17ClN4O2, and its structure consists of an indole group, a thalidomide moiety, and an imidazolidine-2,4-dione ring.