Product Name |
Apixaban Acid-13C |
Alternate Names |
Apixaban Stable Isotopes, Stable Isotopes of Apixaban |
CAT No. |
CS-F-00053
|
CAS No. |
503614-92-4(Unlabelled) |
Category |
Stable Isotopes |
Stock |
Enquire
|
Mol. Wt. |
461.47 g/mol |
Mol. For. |
C24¹³CH24N4O5
|
Hazardous |
This is not a Hazardous Compound
|
COA |
View Sample COA
|
MSDS |
View Sample MSDS
|
Parent API |
Apixaban |
Controlled |
No |
Shipping |
Free for purchase above 1000$ |
Delivery |
In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
Return |
Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
Ordering |
Place your order online or by email sales@clearsynth.com |
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Apixaban Acid-13C is a stable isotope labeled analog of Apixaban, a novel oral anticoagulant used for the treatment and prevention of thromboembolic disorders. Apixaban Acid-13C is synthesized with a high degree of isotopic purity and is commonly used in pharmacokinetic studies to evaluate the metabolic fate of Apixaban.
Apixaban Acid-13C belongs to a class of drugs known as direct oral anticoagulants (DOACs), which inhibit the activity of Factor Xa, a key enzyme involved in the blood clotting cascade. By inhibiting Factor Xa, Apixaban Acid-13C effectively prevents the formation of blood clots, thereby reducing the risk of stroke, deep vein thrombosis, and pulmonary embolism.
The chemical formula of Apixaban Acid-13C is C25H22C13N5O4S, and its molecular weight is 555.6 g/mol. It is a white to off-white crystalline powder that is soluble in organic solvents such as methanol and dimethyl sulfoxide.
Apixaban Acid-13C is metabolized primarily in the liver by cytochrome P450 enzymes, and its half-life is approximately 12 hours. The pharmacokinetics of Apixaban Acid-13C are similar to those of Apixaban, and it is excreted primarily in the feces.
In conclusion, Apixaban Acid-13C is a valuable tool for investigating the pharmacokinetics and metabolism of Apixaban, a widely used anticoagulant. Its stable isotopic labeling allows for accurate and sensitive detection in biological samples, making it an essential component of drug development and clinical research.