Aldosterone D4

Aldosterone D4 is a stable isotope-labeled version of aldosterone, a steroid hormone that plays a crucial role in regulating electrolyte and water balance in the body. It is synthesized and secreted by the adrenal cortex in response to various physiological stimuli, such as low blood pressure, low blood volume, and high potassium levels. Aldosterone D4 is commonly used as an internal standard in mass spectrometry-based assays to quantify aldosterone levels in biological samples. It has the same chemical and physical properties as aldosterone but contains four additional deuterium atoms, which makes it distinguishable from the endogenous hormone. This allows for accurate and precise measurements of aldosterone concentrations, which can provide valuable information about the functioning of the renin-angiotensin-aldosterone system (RAAS). Chemically, aldosterone D4 is a steroid hormone that belongs to the mineralocorticoid class of hormones. It is synthesized from cholesterol and acts on mineralocorticoid receptors in the kidney, colon, and sweat glands, causing them to reabsorb sodium and excrete potassium. This leads to an increase in blood volume and blood pressure, which helps to maintain homeostasis in the body. In conclusion, aldosterone D4 is an important tool for researchers and clinicians alike, as it allows for accurate and sensitive measurements of aldosterone levels. Its chemical properties and physiological effects make it a valuable compound for studying electrolyte and water balance, hypertension, and other related conditions.