17α-Hydroxypregnenolone-[13C2,d2]

17α-Hydroxypregnenolone-[13C2,d2] is a synthetic compound that is used in medical research to study the biosynthesis and metabolism of steroid hormones in the human body. It is a labeled form of 17α-hydroxypregnenolone, which is a natural steroid hormone that is produced in the adrenal glands and gonads. The compound is labeled with two carbon-13 atoms and two deuterium atoms, which makes it useful for tracing the metabolic fate of the hormone in vivo. In terms of chemical structure, 17α-Hydroxypregnenolone-[13C2,d2] is a pregnane steroid that contains a hydroxyl group at the 17α position. The additional carbon and deuterium atoms are incorporated into the molecule to provide a unique signature that can be detected and quantified using mass spectrometry. Researchers use 17α-Hydroxypregnenolone-[13C2,d2] to study the biosynthesis of steroid hormones, including cortisol, aldosterone, and testosterone. By tracing the metabolic fate of the labeled compound, researchers can gain insights into the mechanisms of hormone synthesis and regulation. Additionally, 17α-Hydroxypregnenolone-[13C2,d2] can be used to study the metabolism of steroids in various disease states, such as adrenal insufficiency and adrenal tumors. Overall, 17α-Hydroxypregnenolone-[13C2,d2] is a valuable tool for medical research that provides unique insights into the biosynthesis and metabolism of steroid hormones.