2-Methoxy-[13C,d3]-estradiol

2-Methoxy-[13C,d3]-estradiol is a labeled derivative of the natural hormone 17β-estradiol, which plays a vital role in the female reproductive system. As a labeled compound, it is widely used in scientific research to study the metabolism, pharmacokinetics, and biological activity of estradiol. The chemical formula of 2-Methoxy-[13C,d3]-estradiol is C20H23D3O3[13C]H3, and it has a molecular weight of 319.46 g/mol. The compound is stable under normal conditions and is soluble in common organic solvents like methanol, ethanol, and dimethyl sulfoxide. In terms of usage, 2-Methoxy-[13C,d3]-estradiol is a valuable tool in the study of estrogen receptor-mediated signaling pathways and their involvement in various diseases like breast cancer and osteoporosis. It is also used in the development of novel drugs that target estrogen receptors. The labeled compound is typically administered to cells or animals via injection or oral gavage, and its distribution and metabolism are monitored using various analytical techniques like liquid chromatography-mass spectrometry (LC-MS) and nuclear magnetic resonance (NMR) spectroscopy. In conclusion, 2-Methoxy-[13C,d3]-estradiol is a useful compound in scientific research and drug development, providing valuable insights into the role of estrogen receptors in health and disease.