4-Methoxy-[13C,d3]-estradiol

4-Methoxy-[13C,d3]-estradiol is a derivative of the hormone, estradiol, which is naturally produced by the ovaries and plays a vital role in the regulation of the female reproductive system. This particular derivative contains a stable isotope of carbon and deuterium, making it useful in research and diagnostic applications. 4-Methoxy-[13C,d3]-estradiol is primarily used in studies focused on understanding the mechanisms involved in estrogen receptor binding and activation. Additionally, it is used in studies investigating the metabolism and pharmacokinetics of estradiol in vivo. By utilizing this stable isotope-labeled derivative, researchers can accurately measure the levels of estradiol and its metabolites in various biological samples. Chemically, 4-Methoxy-[13C,d3]-estradiol is a synthetic estrogen that is structurally similar to estradiol. It is a white crystalline powder that is soluble in organic solvents such as ethanol and dichloromethane. Its molecular formula is C20H21O3 and its molecular weight is 321.38 g/mol. 4-Methoxy-[13C,d3]-estradiol is typically synthesized using a combination of chemical and enzymatic methods. In summary, 4-Methoxy-[13C,d3]-estradiol is a useful tool in estrogen-related research due to its stable isotope labeling and similarity to natural estradiol. Its chemical properties and structure make it a valuable tool for investigating the mechanisms involved in estrogen receptor binding and activation, as well as the metabolism and pharmacokinetics of estradiol in vivo.