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6-Methylthioguanine-[13C,d3] is a stable isotope labeled analogue of the naturally occurring nucleobase guanine. It has the chemical formula C6H3N5O2S and has a molecular weight of 201.21 g/mol. The compound is a yellowish powder that is soluble in water and has a melting point of 231-235°C.
6-Methylthioguanine-[13C,d3] is commonly used as a reference standard in various analytical applications such as mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. The stable isotopes in the compound allow for accurate quantification and identification of the compound in complex biological samples. It is also used in metabolic labeling studies to track the fate of guanine in biological systems.
In terms of its chemical properties, 6-Methylthioguanine-[13C,d3] is a purine derivative that is structurally similar to guanine. It has a methylthio group (-S-CH3) attached to the sixth carbon atom of the purine ring. The stable isotopes in the compound are present at the carbon-13 and deuterium atoms, respectively. These isotopes do not significantly alter the chemical properties of the compound, but they do allow for the compound to be easily distinguished from its non-labeled counterparts.
Overall, 6-Methylthioguanine-[13C,d3] is a useful tool in various analytical and metabolic labeling studies that require accurate quantification and identification of guanine derivatives. Its stable isotope labeling allows for specific detection and tracking of the compound in complex biological systems.
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