Ruxolitinib, SEM pyrimidine impurity
| Product Name | Ruxolitinib, SEM pyrimidine impurity |
|---|---|
| Alternate Names | Ruxolitinib Impurities, Impurities of Ruxolitinib |
| CAT No. | CS-M-24045 |
| CAS No. | 941685-27-4 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 315.45 g/mol |
| Mol. For. | C₁₅H₂₁N₅OSi |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Ruxolitinib |
| Canonical Smiles | C[Si](C)(C)CCOCN1C=CC2=C(N=CN=C21)C3=CNN=C3 |
| InchIKey | AVMLPTWVYQXRSV-UHFFFAOYSA-N |
| Inchl | InChI=1S/C15H21N5OSi/c1-22(2,3)7-6-21-11-20-5-4-13-14(12-8-18-19-9-12)16-10-17-15(13)20/h4-5,8-10H,6-7,11H2,1-3H3,(H,18,19) |
| IUPAC | trimethyl-[2-[[4-(1H-pyrazol-4-yl)pyrrolo[2,3-d]pyrimidin-7-yl]methoxy]ethyl]silane |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine is a chemical compound that belongs to the family of pyrrolopyrimidine derivatives. This compound has a molecular formula of C17H25N5OSi and a molecular weight of 359.48 g/mol.
This compound is commonly used in biomedical research as a potential inhibitor of certain enzymes involved in cancer cell growth and proliferation. It has been shown to selectively inhibit the activity of a protein kinase called CDK7, which plays an important role in the regulation of cell cycle progression and transcriptional control. CDK7 inhibition has been suggested as a potential therapeutic strategy for various types of cancer.
The chemical structure of 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine contains a pyrrolopyrimidine core, which is fused to a pyrazole ring and a trimethylsilyl group. The trimethylsilyl group is important for the stability and solubility of the compound, as well as for its pharmacological activity.
Overall, 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine is a promising compound for cancer research and drug development, owing to its potent and selective inhibition of CDK7 activity. Further studies are needed to fully understand its mechanism of action and potential therapeutic applications.
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Related Compounds
Ruxolitinib Phosphate | Ruxolitinib SEM-Sulfonyl Impurity | N-Nitroso Ruxolitinib Amide | Rac-Ruxolitinib Acrylo pyrimidine Impurity | Acetamide Baricitinib Impurity | Rac-5-hydroxymethyl Ruxolitinib impurity | Ruxolitinib Nitroso Impurity 3 | Ruxolitinib Acid impurity | Ruxolitinib Hydroxy Impurity | Ruxolitinib Impurity 7 | Ruxolitinib Amide impurity | Ruxolitinib Nitroso Impurity 2 | Ruxolitinib carboxamide impurity | Ruxolitinib SEM impurity | Rac-Ruxolitinib-amide | Ruxolitinib Impurity 4 | Ruxolitinib N-Methanol | RUXOLITINIB SEM TARTARIC ACID S-ISOMER | Ruxolitinib S-isomer Oxalate | Ruxolitinib Enantiomer | Ruxolitinib N-Oxide Impurity 1 | Ruxolitinib Methyl ester impurity | Rac-Ruxolitinib N-acetylymethyl impurity | Ruxolitinib M27 | Ruxolitinib Lactone Impurity | Ruxolitinib Nitroso Impurity 4 | Ruxolitinib Vinyl dimer impurity | N-nitroso Ruxolitinib | N-Nitroso of KSM-I | Ruxolitinib Dibenzoyl SME Pyrimidine Impurity | Ruxolitinib acid amine impurity | Ruxolitinib M18 | Ruxolitinib dimethylamine impurity |