Methotrexate EP Impurity B

Product Name Methotrexate EP Impurity B
Alternate Names Methotrexate Impurities, Impurities of Methotrexate
CAT No. CS-M-42743
CAS No. 54-62-6
Category Impurities
Stock Enquire
Mol. Wt. 440.4 g/mol
Mol. For. C19H20N8O5
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Methotrexate
Therapeutic Immunosuppressants, Anti Neo Plastic Agents
Smileys C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=NC(=N3)N)N
Canonical Smiles C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=NC(=N3)N)N
InchIKey TVZGACDUOSZQKY-LBPRGKRZSA-N
Inchl InChI=1S/C19H20N8O5/c20-15-14-16(27-19(21)26-15)23-8-11(24-14)7-22-10-3-1-9(2-4-10)17(30)25-12(18(31)32)5-6-13(28)29/h1-4,8,12,22H,5-7H2,(H,25,30)(H,28,29)(H,31,32)(H4,20,21,23,26,27)/t12-/m0/s1
IUPAC (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
Controlled No
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Methotrexate EP Impurity B is a chemical compound that is used in various scientific and medical research applications. It is a structural isomer of Methotrexate, which is a widely used chemotherapy drug. Methotrexate EP Impurity B is primarily used as a reference standard in the development and validation of analytical methods for the quantitative analysis of Methotrexate and related compounds. Chemically, Methotrexate EP Impurity B is a diastereoisomer of Methotrexate that differs in the configuration of one of its chiral centers. It has a molecular formula of C20H22N8O5 and a molecular weight of 462.44 g/mol. It is a white to off-white crystalline powder that is soluble in water and methanol. Methotrexate EP Impurity B is typically used in pharmaceutical laboratories to test for the purity and potency of Methotrexate products. It is also used in pharmacokinetic studies to determine the metabolism and elimination of Methotrexate in the body. In conclusion, Methotrexate EP Impurity B is a valuable chemical compound that plays a crucial role in the development and validation of analytical methods for the quantitative analysis of Methotrexate and related compounds. Its chemical properties and applications make it an essential reference standard for pharmaceutical research and development.

Related Compounds

N-Desmethyl Methotrexate dinitroso impurity | Methotrexate EP Impurity D | N-Nitroso Methotrexate EP Impurity-B | Methotrexate EP Impurity I | N-nitroso Methotrexate Ethylester impurity | Methotrexate diethyl ester | Methotrexate EP Impurity J | Methotrexate EP Impurity E | Methotrexate EP Impurity B Disodium salt | Methotrexate EP Impurity L | Methotrexate Dimethylamide | Methotrexate EP Impurity G | Methotrexate Nitroso Impurity 1 | N-Dinitroso Methotrexate Impurity 2 | Methotrexate - Impurity E (HCl Salt) | R-Methotrexate di sodium | Methotrexate Nitroso Impurity 1 | Methotrexate EP Impurity H | Methotrexate EP Impurity A | Methotrexate EP Impurity F | N-Nitroso Methotrexate EP Impurity-L (2) | N, N-Dinitroso Methotrexate EP Impurity L | Methotrexate EP Impurity C | Methotrexate EP Impurity B (MonoHydrate) | N-Nitroso Methotrexate EP Impurity-L (1) | N-nitroso Methotrexate Impurity 2 |

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