2-Thioadenosine

Product Name 2-Thioadenosine
Alternate Names Adenosine Impurities, Impurities of Adenosine
CAT No. CS-N-00289
CAS No. 43157-50-2
Category Impurities
Stock IN-Stock
Mol. Wt. Not Available
Mol. For. C10H12N4O4S
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Adenosine
Smileys NC(N1)=C(N=CN2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC1=S
Canonical Smiles C1=NC2=C(NC(=S)N=C2N1C3C(C(C(O3)CO)O)O)N
InchIKey LTESOZAUMTUKQX-UUOKFMHZSA-N
Inchl InChI=1S/C10H13N5O4S/c11-7-4-8(14-10(20)13-7)15(2-12-4)9-6(18)5(17)3(1-16)19-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,20)/t3-,5-,6-,9-/m1/s1
IUPAC 6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purine-2-thione
Controlled No
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2-Thioadenosine, also known as 2-TA, is a naturally occurring nucleoside that plays a crucial role in many biochemical processes. It is a sulfur-containing analogue of the well-known molecule adenosine, which is a building block of RNA and DNA. This molecule is found in various biological systems, including bacteria, yeast, and mammals. The primary usage of 2-Thioadenosine is in the study of cellular metabolism and signal transduction pathways. It has been shown to have anti-inflammatory and immunomodulatory properties, making it a promising candidate for the development of new therapeutics. Additionally, 2-Thioadenosine has been found to have antiviral activity against hepatitis C and human immunodeficiency virus (HIV). It is also used as a research tool to study the effects of purinergic signaling on immune cell function. From a chemical perspective, 2-Thioadenosine is a nucleoside composed of a ribose sugar, an adenine base, and a thiol group (-SH) instead of a hydroxyl group (-OH) at the 2' carbon of the ribose. This modification alters the molecule's properties, making it less susceptible to degradation by adenosine deaminase, an enzyme that breaks down adenosine. The thiol group also allows for potential interactions with other biomolecules, such as metal ions, which may play a role in its biological activity. Overall, 2-Thioadenosine is a versatile molecule with promising therapeutic potential and continues to be an important tool in biochemical research.

Related Compounds

Adenosine EP Impurity A Potassium Salt | N-Benzoyl-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-O-(2-methoxyethyl)-adenosine | N6-Cyclohexyladenosine | Adenosine 5'-(3,4-diformylbenzoate) | ADENOSINE RIBOSE-1-D | N6-Methyladenosine | N6-Propargyladenosine | Dideoxy Adenosine | ADENOSINE RIBOSE-2-D | N6-Benzyl Adenosine | N6-Benzyl-5-ethylcarboxamido Adenosine | Adenosine 5'-Monophosphoramidate | N6-(2-Hydroxyethyl)-2'-deoxyadenosine | Adenosine 5'-Triphosphate | Adenosine EP Impurity A Hydrobromide | N6-Formyl-adenosine | Adenosine-3',5'-cyclic Monophosphate |

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