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Desipramine Hydrochloride

Also known as: Desipramine Impurities or impurities of Desipramine
Chemical Name Desipramine Hydrochloride
CAT No. CS-O-00278
CAS Registry# 58-28-6
Status Under Certification (Usually dispatched in 5 days)
Category Impurities
Mol. Wt. 266.4 : 36.5 g/mol
Mol. For. C18H22N2 : HCl
Hazardous This is a Hazardous Compound
COA View Sample COA

Additional Information


Controlled No
Parent API Desipramine
Purity Not less than 95%
Therapeutic Nervous system drugs
Smileys CNCCCN1C2=CC=CC=C2CCC3=CC=CC=C31.Cl
Canonical Smiles CNCCCN1C2=CC=CC=C2CCC3=CC=CC=C31.Cl
InchIKey XAEWZDYWZHIUCT-UHFFFAOYSA-N
Inchl InChI=1S/C18H22N2.ClH/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20;/h2-5,7-10,19H,6,11-14H2,1H3;1H
IUPAC 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine;hydrochloride
Hazardous Yes


Usage and description


Desipramine Hydrochloride is a medication used to treat depression, anxiety disorders, and attention-deficit hyperactivity disorder. It belongs to the class of drugs known as tricyclic antidepressants, which work by increasing the levels of certain neurotransmitters in the brain, such as serotonin and norepinephrine. Desipramine Hydrochloride is typically administered orally in the form of tablets or capsules, and the dosage is determined by the patient's age, weight, and medical condition. The medication is typically taken once or twice a day, with or without food. Chemically, Desipramine Hydrochloride is a white crystalline powder that is soluble in water and alcohol. It has a molecular formula of C18H22N2.HCl and a molecular weight of 302.84 g/mol. The medication is highly selective for the norepinephrine transporter and has minimal affinity for other receptors in the brain. Desipramine Hydrochloride is metabolized in the liver and excreted in the urine. The medication has a half-life of approximately 20 hours and can take several weeks to reach therapeutic levels in the bloodstream. As with any medication, Desipramine Hydrochloride may cause side effects, including dry mouth, constipation, blurred vision, dizziness, and weight gain. It may also interact with other medications, so it is important to consult with a healthcare provider before taking Desipramine Hydrochloride.

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