Trimetazidine D8 dihydrochloride
| Product Name | Trimetazidine D8 dihydrochloride |
|---|---|
| Alternate Names | Trimetazidine Stable Isotopes, Stable Isotopes of Trimetazidine |
| CAT No. | CS-O-00739 |
| CAS No. | 1219795-37-5 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 347.31 g/mol |
| Mol. For. | C₁₄H₁₆D₈Cl₂N₂O₃ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Trimetazidine |
| Purity | 95% |
| Smileys | COC1=C(C=CC(OC)=C1OC)CN2C([2H])([2H])C([2H])([2H])NC([2H])([2H])C2([2H])[2H].Cl.Cl |
| Canonical Smiles | COC1=C(C(=C(C=C1)CN2CCNCC2)OC)OC.Cl.Cl |
| InchIKey | VYFLPFGUVGMBEP-IKGFOUCPSA-N |
| Inchl | InChI=1S/C14H22N2O3.2ClH/c1-17-12-5-4-11(13(18-2)14(12)19-3)10-16-8-6-15-7-9-16;;/h4-5,15H,6-10H2,1-3H3;2*1H/i6D2,7D2,8D2,9D2;; |
| IUPAC | 2,2,3,3,5,5,6,6-octadeuterio-1-[(2,3,4-trimethoxyphenyl)methyl]piperazine;dihydrochloride |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Trimetazidine D8 dihydrochloride is a deuterated form of trimetazidine hydrochloride, which is a medication used for the treatment of angina pectoris. Trimetazidine D8 dihydrochloride is a stable isotope-labeled compound, with eight deuterium atoms replacing eight hydrogen atoms in the molecular structure of trimetazidine hydrochloride.
Trimetazidine D8 dihydrochloride is a selective inhibitor of mitochondrial long-chain 3-ketoyl coenzyme A thiolase, which is involved in the beta-oxidation of fatty acids. By inhibiting this enzyme, trimetazidine D8 dihydrochloride helps to shift the metabolism of cardiac cells from fatty acid oxidation to glucose oxidation, thereby improving the energy efficiency of the heart and reducing the risk of ischemia.
Trimetazidine D8 dihydrochloride is typically administered orally, and the recommended dosage varies depending on the severity of the angina and the patient's individual response to the medication. The drug is metabolized in the liver and excreted in the urine, with a half-life of approximately 7 hours.
While trimetazidine D8 dihydrochloride is generally well-tolerated, it may cause side effects such as dizziness, nausea, and headache. It may also interact with other medications, so it is important to consult with a healthcare provider before using this medication. Overall, trimetazidine D8 dihydrochloride is a useful medication for the management of angina pectoris, and its stable isotope-labeled form may have applications in pharmacokinetic studies and drug metabolism research.
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Related Compounds
N-Nitroso Trimetazidine D9 | N-(Methyl-d3) Trimetazidine Dihydrochloride | N-Nitroso Trimetazidine-d9 HCl | N-Methyl Trimetazidine-d8 Dihydrochloride | Trimetazidine D9 | N-Nitroso Trimetazidine D8 |