(S)-Lisinopril D5

Product Name (S)-Lisinopril D5
Alternate Names Lisinopril Stable Isotopes, Stable Isotopes of Lisinopril
CAT No. CS-O-00742
CAS No. 1356905-39-9
Category Stable Isotopes
Stock Enquire
Mol. Wt. 410.52 g/mol
Mol. For. C21H26D5N3O5
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Lisinopril
Purity 98.52
Therapeutic Anti-Hypertensives
Smileys O=C(N(CCC1)[C@@H]1C(O)=O)[C@H](CCCCN)N[C@H](C(O)=O)CCC(C([2H])=C2[2H])=C(C([2H])=C2[2H])[2H]
Canonical Smiles C1CC(N(C1)C(=O)C(CCCCN)NC(CCC2=CC=CC=C2)C(=O)O)C(=O)O
InchIKey RLAWWYSOJDYHDC-MMUMHYRKSA-N
Inchl InChI=1S/C21H31N3O5/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29)/t16-,17-,18-/m0/s1/i1D,2D,3D,7D,8D
IUPAC (2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-(2,3,4,5,6-pentadeuteriophenyl)propyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid
Controlled No
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(S)-Lisinopril D5 is a deuterium-labeled version of the ACE inhibitor drug Lisinopril. It is primarily used for treating high blood pressure, heart failure, and to improve survival after a heart attack. This medication works by relaxing blood vessels, which in turn lowers blood pressure and improves blood flow to the heart. The deuterium-labeled version, (S)-Lisinopril D5, is used in pharmacokinetic studies to determine how the drug is absorbed, distributed, metabolized, and eliminated from the body. This is important in understanding the efficacy and safety of the drug. Chemically, (S)-Lisinopril D5 is a synthetic peptide derivative consisting of 10 amino acids. It is a prodrug, meaning it is inactive until it is converted in the liver to its active form. The deuterium label is used in studies to differentiate the drug from its non-labeled counterpart, allowing researchers to track the drug’s movement through the body. (S)-Lisinopril D5 is typically administered orally and is available in tablet form. It is important to note that this medication should only be taken as prescribed by a healthcare professional. Common side effects may include dizziness, headache, and cough. In rare cases, more serious side effects such as kidney problems or allergic reactions may occur. In conclusion, (S)-Lisinopril D5 is an important tool in pharmacokinetic studies and is used to treat a variety of cardiovascular conditions. Its chemical structure and deuterium label allow for detailed research into the drug’s effects and safety. As with any medication, it should only be taken as directed by a healthcare professional.

Related Compounds

N-Nitroso Lisinopril D5 | LISINOPRIL D5 DIHYDROCHLORIDE | Lisinopril 13C5,15N | N-Nitroso Lisinopril D5 TFA salt | Lisinopril D5 |

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