Propafenone-d5 (phenyl-d5) hydrochloride

Propafenone-d5 (phenyl-d5) hydrochloride is a deuterated version of propafenone hydrochloride, which is a class Ic antiarrhythmic drug used to treat irregular heartbeats and arrhythmias. This medication works by slowing down the electrical signals that control the heart's rhythm, allowing it to beat more regularly. Like propafenone hydrochloride, propafenone-d5 (phenyl-d5) hydrochloride is available in oral tablet form and is typically taken two to three times per day. The dosage is determined based on a patient's weight, medical history, and the severity of their condition. It is important to take this medication exactly as prescribed by a doctor, as skipping doses or taking too much can lead to adverse effects. Chemically, propafenone-d5 (phenyl-d5) hydrochloride is a deuterated compound, meaning that some of the hydrogen atoms in the molecule have been replaced with deuterium atoms. This modification does not significantly alter the drug's mechanism of action, but it can change the way it is metabolized and eliminated from the body. Propafenone-d5 (phenyl-d5) hydrochloride is metabolized in the liver and excreted primarily in the urine. It has a half-life of approximately six hours, meaning that it takes about six hours for half of the drug to be eliminated from the body. This medication should not be taken by individuals with certain medical conditions, such as severe liver or kidney disease, or by those who are allergic to propafenone or any of its components.