Sildenafil-N-Oxide
| Product Name | Sildenafil-N-Oxide |
|---|---|
| Alternate Names | Sildenafil Impurities, Impurities of Sildenafil |
| CAT No. | CS-O-01446 |
| CAS No. | 1094598-75-0 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 490.58 g/mol |
| Mol. For. | C₂₂H₃₀N₆O₅S |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Sildenafil |
| Purity | 95% |
| Therapeutic | Erectile dysfunction |
| Smileys | CCOC1=C(C(NC2=C3N(C)N=C2CCC)=NC3=O)C=C([S](=O)(N(CC4)CC[N]4(C)=O)=O)C=C1 |
| Canonical Smiles | CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CC[N+](CC4)(C)[O-])OCC)C |
| InchIKey | JQGFLCMKCZPSEC-UHFFFAOYSA-N |
| Inchl | InChI=1S/C22H30N6O5S/c1-5-7-17-19-20(26(3)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)33-6-2)34(31,32)27-10-12-28(4,30)13-11-27/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29) |
| IUPAC | 5-[2-ethoxy-5-(4-methyl-4-oxidopiperazin-4-ium-1-yl)sulfonylphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Sildenafil-N-Oxide is a chemical compound that is structurally related to Sildenafil, a medication used to treat erectile dysfunction and pulmonary arterial hypertension. Sildenafil-N-Oxide is a derivative of Sildenafil, and it is believed to be a metabolite of Sildenafil that is formed in the liver. It is a potent inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5), which is the same mechanism of action as Sildenafil.
The chemical formula of Sildenafil-N-Oxide is C22H30N6O4S, and its molecular weight is 478.58 g/mol. It is a white to off-white powder that is soluble in water, ethanol, and dimethyl sulfoxide (DMSO). Sildenafil-N-Oxide is not approved for use in humans, and there is limited research available on its pharmacokinetics and pharmacodynamics.
Sildenafil-N-Oxide may be used in research studies to investigate the metabolism and pharmacology of Sildenafil. It may also be used as a reference standard for analytical methods used to quantify Sildenafil and its metabolites in biological samples. However, caution should be exercised when handling Sildenafil-N-Oxide as it is a potent inhibitor of PDE5 and may have adverse effects on cardiovascular function.
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Related Compounds
Demethylpiperazinyl Desethyl Sildenafil Sulfonyl Chloride | Propoxyphenyl Sildenafil | Sildenafil Citrate Impurity-1 | N-(Desmethyl)-tert-butyl Acetate Sildenafil | Propoxyphenyl Thiosildenafil | Sildenafil Related Compound | Dimethylsildenafil | Thiohomo Sildenafil | Sildenafil Methyl Sulfonate Ester Impurity | Sildenafil EP Impurity E | Sildenafil Dimer Impurity | Demethylpiperazinyl 7-Desoxo 7-Thioxosildenafil Sulfonic Acid | Sildenafil Impurity 3 | Propoxyphenyl Homohydroxysildenafil | O-Desethyl-O-propyl Methisosildenafil | Sildenafil Citrate Impurity 3 | Demethylpiperazinyl Iso Sildenafil Sulfonyl Chloride | Sildenafil Chlorosulfone | Norneo Sildenafil | Desmethyl Thiosildenafil | Pyrazole N-Demethyl Sildenafil | Benzyl Sildenafil | De(methypiperazinyl) Sildenafil Dimer Impurity | Sildenafil EP Impurity D | Nitroso-prodenafil | N-Nitroso N-desmethyl Sildenafil | Descarbonsildenafil | N-Nitroso Sildenafil | Hydroxythiohomo Sildenafil | Sildenafil Citrate Impurity 2 | Sildenafil open ring Impurity | Sildenafil Impurity A | Hydroxyhomo Sildenafil | Propoxyphenyl-thiohydroxyhomosildenafil |