Ketorolac tromethamine

Product Name Ketorolac tromethamine
Alternate Names Ketorolac Impurities, Impurities of Ketorolac
CAT No. CS-O-01710
CAS No. 74103-07-4
Category Impurities
Stock IN-Stock
Mol. Wt. 376.40 g/mol
Mol. For. C₁₉H₂₄N₂O₆
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Ketorolac
Purity Not less than 95 %
Therapeutic Anti-Migraines
Smileys C1CN2C(=CC=C2C(=O)C3=CC=CC=C3)C1C(=O)O.C(C(CO)(CO)N)O
Canonical Smiles C1CN2C(=CC=C2C(=O)C3=CC=CC=C3)C1C(=O)O.C(C(CO)(CO)N)O
InchIKey BWHLPLXXIDYSNW-UHFFFAOYSA-N
Inchl InChI=1S/C15H13NO3.C4H11NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13;5-4(1-6,2-7)3-8/h1-7,11H,8-9H2,(H,18,19);6-8H,1-3,5H2
IUPAC 2-amino-2-(hydroxymethyl)propane-1,3-diol;5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
Controlled No
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Ketorolac tromethamine is a nonsteroidal anti-inflammatory drug (NSAID) used to treat moderate to severe pain. It works by blocking the production of prostaglandins, which are responsible for inflammation, pain, and fever. Ketorolac tromethamine is commonly used after surgery, dental procedures, and for the treatment of menstrual cramps, arthritis, and sports injuries. Chemically, Ketorolac tromethamine is a white, crystalline powder that is soluble in water and has a melting point of 162-165°C. It is a racemic mixture of R and S enantiomers, with the S enantiomer being more potent than the R enantiomer. The drug is rapidly absorbed after oral administration and reaches peak plasma levels within 1-2 hours. Ketorolac tromethamine is available in various forms, including tablets, injections, and eye drops. The dosage and duration of treatment depend on the patient's condition and response to therapy. However, it should not be used for more than five days due to the risk of serious side effects such as gastrointestinal bleeding, kidney damage, and allergic reactions. In conclusion, Ketorolac tromethamine is a potent NSAID that is widely used for pain relief. Its chemical properties and mechanism of action make it an effective analgesic and anti-inflammatory agent. However, its use should be closely monitored to avoid the risk of complications.

Related Compounds

Ketorolac EP Impurity C | Ketorolac EP Impurity J | Ketorolac 1-Keto Analog | Ketorolac EP Impurity G | Ketorolac EP Impurity F | Ketorolac EP Impurity H | N-(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)-N-methylnitrous amide | Ketorolac EP Impurity E | Ketorolac EP Impurity B | N-(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)-N-hydroxynitrous amide | Ketorolac EP Impurity D | Ketorolac EP Impurity I | Ketorolac EP Impurity A | Bromo ketorolac | N-Nitroso Ketorolac 2-Benzoylpyrrole Impurity | N-Nitroso Ketorolac Triethylester Intermediate |

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