Omeprazole D3 (5-methoxy-d3)

Omeprazole D3 is a deuterated form of omeprazole, a proton-pump inhibitor that is commonly used to treat conditions such as gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger-Ellison syndrome. Omeprazole D3 is chemically identical to omeprazole, except that three of its hydrogen atoms have been replaced with deuterium atoms. The use of Omeprazole D3 is primarily in research settings, particularly in pharmacokinetic studies, to help track and quantify the drug's distribution and metabolism in the body. The presence of deuterium in the drug molecule can help researchers differentiate it from endogenous compounds and other drugs in the body, allowing for more accurate measurements. Omeprazole D3 has a similar mechanism of action to omeprazole, working by inhibiting the activity of the H+/K+ ATPase enzyme in the stomach lining, which reduces the amount of acid produced. This leads to a reduction in the symptoms of GERD and other related conditions. The drug is usually taken orally in the form of capsules, and the recommended dosage and frequency of use will depend on the specific condition being treated. Overall, Omeprazole D3 is a useful tool for researchers studying the pharmacokinetics of omeprazole and related drugs. Its chemical similarity to omeprazole ensures that its effects will be comparable, while its deuterium content allows for more precise measurements. However, it is not intended for use as a medication in itself and should only be used for research purposes.