Perindopril D4
| Product Name | Perindopril D4 |
|---|---|
| Alternate Names | Perindopril Stable Isotopes, Stable Isotopes of Perindopril |
| CAT No. | CS-O-02626 |
| CAS No. | 1356929-58-2 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 372.5 g/mol |
| Mol. For. | C19H28D4N2O5 |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Perindopril |
| Purity | 98.64 |
| Therapeutic | Anti-Hypertensives |
| Smileys | O=C(N1[C@](CCCC2)([H])[C@]2([H])C[C@H]1C(O)=O)[C@@](C([2H])([2H])[2H])([2H])N[C@@H](CCC)C(OCC)=O |
| Canonical Smiles | CCCC(C(=O)OCC)NC(C)C(=O)N1C2CCCCC2CC1C(=O)O |
| InchIKey | IPVQLZZIHOAWMC-UQXGGBCESA-N |
| Inchl | InChI=1S/C19H32N2O5/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24/h12-16,20H,4-11H2,1-3H3,(H,23,24)/t12-,13-,14-,15-,16-/m0/s1/i3D3,12D |
| IUPAC | (2S,3aS,7aS)-1-[(2S)-2,3,3,3-tetradeuterio-2-[[(2S)-1-ethoxy-1-oxopentan-2-yl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Perindopril D4 is a deuterated analogue of the drug Perindopril, which is primarily used in the treatment of hypertension and congestive heart failure. Deuterated compounds are isotopically modified versions of their non-deuterated counterparts, where one or more hydrogen atoms are replaced by deuterium atoms. These modifications can improve the drug's efficacy and safety profile, as well as its pharmacokinetic properties.
Perindopril D4 works by inhibiting the enzyme angiotensin-converting enzyme (ACE), which plays a role in regulating blood pressure. By blocking this enzyme, Perindopril D4 helps to widen blood vessels and reduce resistance, thereby lowering blood pressure and improving blood flow. It is typically administered orally as a tablet, and its effects can be seen within a few hours of administration.
In terms of chemical information, Perindopril D4 has a molecular formula of C19H24D4N2O5 and a molecular weight of 384.50 g/mol. Its structure consists of a carboxylic acid group, an amine group, and a peptide-like structure that mimics the structure of the natural substrate of ACE. This structure allows Perindopril D4 to bind to the active site of ACE and inhibit its activity.
In conclusion, Perindopril D4 is a deuterated analogue of the drug Perindopril that is used in the treatment of hypertension and congestive heart failure. Its chemical structure and mechanism of action make it an effective and safe treatment option for these conditions.
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Related Compounds
Perindopril-13C3 | Perindopril-d4 t-Butylamine Salt | Perindopril Diketopiperazine-d4 | Perindopril 13C3 | Perindopril-d4 Acyl-α-D-glucuronide | Perindoprilat D4 | Perindopril-13C3 t-Butylamine Salt | Perindopril D4 HCl | Perindopril-D5 |