Losartan D4

Product Name Losartan D4
Alternate Names Losartan Stable Isotopes, Stable Isotopes of Losartan
CAT No. CS-O-02637
CAS No. 1030937-27-9
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 426.94 g/mol
Mol. For. C₂₂H₁₉D₄ClN₆O
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Losartan
Purity 95%
Therapeutic Anti-Hypertensives
Smileys OCC1=C(Cl)N=C(CCCC)N1CC(C([2H])=C2[2H])=C(C([2H])=C2C3=C(C4=NN=NN4)C=CC=C3)[2H]
Canonical Smiles CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)CO)Cl
InchIKey PSIFNNKUMBGKDQ-IRYCTXJYSA-N
Inchl InChI=1S/C22H23ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28)/i9D,10D,11D,12D
IUPAC [2-butyl-5-chloro-3-[[2,3,5,6-tetradeuterio-4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
Controlled No
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Losartan D4 is a medication that is used to treat high blood pressure. It is a synthetic angiotensin receptor blocker (ARB) that works by blocking the action of angiotensin II, a hormone that causes blood vessels to narrow and the body to retain water and salt, leading to an increase in blood pressure. Inhibiting the action of angiotensin II causes blood vessels to relax and dilate, which in turn helps to reduce blood pressure. Losartan D4 is chemically similar to the non-deuterated Losartan, but the deuterium atoms give Losartan D4 a slightly different pattern of mass spectra, which can be useful in pharmacokinetic studies. The deuterium labeling also increases the stability of the compound, making it more resistant to metabolic breakdown. The recommended dosage of Losartan D4 varies depending on the severity of the patient's hypertension and other factors such as their age and medical history. It is typically taken once a day orally, with or without food. It is important to follow the instructions provided by the prescribing healthcare provider and to not stop taking Losartan D4 without consulting with them first. Like all medications, Losartan D4 has potential side effects such as dizziness, fatigue, and headache. It is important to monitor for any adverse reactions and to report them to a healthcare provider if they occur. Overall, Losartan D4 is an effective medication for managing hypertension and its unique chemical properties make it a useful tool in pharmacokinetic studies.

Related Compounds

Losartan-d3 Carboxylic Acid | Losartan acid D6 hydrochloride | Losartan azide-d8 | Trityl-Losartan D4 | Losartan D2 | Losartan Carboxylic acid D4 | Losartan D3 | N-Trityl Losartan-d4 Carboxaldehyde |

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