Isradipine D6

Isradipine D6 is a deuterated form of Isradipine, which is a calcium channel blocker used for the treatment of hypertension and angina pectoris. Isradipine D6 is used as a reference standard in pharmacological research and clinical studies. It is a selective inhibitor of L-type calcium channels, which are responsible for the influx of calcium ions into vascular smooth muscle and cardiac muscle cells. By inhibiting the influx of calcium ions, Isradipine D6 reduces the contractility of these muscles, leading to vasodilation and decreased blood pressure. The chemical formula of Isradipine D6 is C19H19D6N3O5, and its molecular weight is 386.47 g/mol. It is a white to off-white crystalline powder that is soluble in water, ethanol, and dimethyl sulfoxide (DMSO). Isradipine D6 is stable under normal storage conditions and is sensitive to light. Isradipine D6 is typically administered orally, and its dosage depends on the severity of the patient's condition. It is recommended to take the medication at the same time each day, with or without food. Patients with liver or kidney disease should consult their physician before taking Isradipine D6. In conclusion, Isradipine D6 is a useful reference standard for pharmacological research and clinical studies. Its selective inhibition of L-type calcium channels makes it an effective treatment for hypertension and angina pectoris. However, patients should always consult their physician before taking any medication.