Efavirenz D5

Product Name Efavirenz D5
Alternate Names Efavirenz Stable Isotopes, Stable Isotopes of Efavirenz
CAT No. CS-O-02671
CAS No. 1132642-95-5
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 320.71 g/mol
Mol. For. C₁₄H₄D₅ClF₃NO₂
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Efavirenz
Purity 95%
Therapeutic Antiretroviral / Anti-HIV
Smileys FC(F)(F)[C@](C1=CC(Cl)=CC=C1NC2=O)(O2)C#CC3([2H])C([2H])([2H])C3([2H])[2H]
Canonical Smiles C1CC1C#CC2(C3=C(C=CC(=C3)Cl)NC(=O)O2)C(F)(F)F
InchIKey XPOQHMRABVBWPR-XWJABCKYSA-N
Inchl InChI=1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)/t13-/m0/s1/i1D2,2D2,8D
IUPAC (4S)-6-chloro-4-[2-(1,2,2,3,3-pentadeuteriocyclopropyl)ethynyl]-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
Controlled No
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Efavirenz D5 is a medication that is commonly used to treat HIV infection. It belongs to a class of drugs called non-nucleoside reverse transcriptase inhibitors (NNRTIs), which work by blocking the activity of the HIV reverse transcriptase enzyme. This enzyme is responsible for converting viral RNA into DNA, which can then be integrated into the host cell's genome and lead to the production of new virus particles. Efavirenz D5 is chemically similar to the non-deuterated version of the drug, Efavirenz. However, it contains five deuterium atoms, which can be used in pharmacokinetic studies to track the drug's metabolism and distribution in the body. This can provide valuable information on the drug's safety and efficacy, as well as help to optimize dosing regimens. The recommended dosage of Efavirenz D5 varies depending on the patient's age, weight, and other medical conditions. It is typically taken once daily, either alone or in combination with other antiretroviral medications. Common side effects of the drug include headache, dizziness, nausea, and rash. Less frequently, it can cause more serious side effects such as liver toxicity or psychiatric symptoms. In conclusion, Efavirenz D5 is an important medication for the treatment of HIV infection, and its chemical properties make it useful for pharmacokinetic studies. However, like all medications, it should be used only under the guidance of a healthcare professional and with careful monitoring for potential side effects.

Related Compounds

rac 7-Hydroxy Efavirenz-d4 (Major) | rac 8,14-Dihydroxy Efavirenz-d4 | rac Efavirenz D4 | Efavirenz 13C6 |

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