Bosentan D4

Product Name Bosentan D4
Alternate Names Bosentan Stable Isotopes, Stable Isotopes of Bosentan
CAT No. CS-O-02687
CAS No. 1065472-77-6
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 555.64 g/mol
Mol. For. C₂₇H₂₅D₄N₅O₆S
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Bosentan
Purity Not less than 90 %
Smileys [2H]C([2H])(C([2H])([2H])OC1=NC(=NC(=C1OC2=CC=CC=C2OC)NS(=O)(=O)C3=CC=C(C=C3)C(C)(C)C)C4=NC=CC=N4)
Canonical Smiles CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4OC
InchIKey GJPICJJJRGTNOD-RZOBCMOLSA-N
Inchl InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)/i16D2,17D2
IUPAC 4-tert-butyl-N-[5-(2-methoxyphenoxy)-2-pyrimidin-2-yl-6-(1,1,2,2-tetradeuterio-2-hydroxyethoxy)pyrimidin-4-yl]benzenesulfonamide
Controlled No
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Bosentan D4 is a deuterated form of bosentan, a medication used to treat pulmonary arterial hypertension (PAH). PAH is a condition where the blood pressure in the arteries leading to the lungs is too high, which can lead to heart failure and other complications. Bosentan D4 works by blocking the action of endothelin, a substance that causes narrowing of blood vessels. The chemical formula of Bosentan D4 is C27H22D4N5O6S, and its molecular weight is 568.64 g/mol. It is a white to off-white powder that is soluble in organic solvents like methanol and dimethyl sulfoxide (DMSO), but only slightly soluble in water. Bosentan D4 is typically administered orally in tablet form, usually twice a day. The dosage may vary depending on the severity of the patient's condition and their body weight. Like all medications, Bosentan D4 can have side effects. Common side effects include headache, flushing, nausea, and diarrhea. More serious side effects may include liver damage, anemia, and decreased blood pressure. Overall, Bosentan D4 is an important medication used to treat PAH, a serious condition that can have life-threatening consequences. Its effectiveness and safety have been well-established through clinical trials and real-world use, making it an important tool in the treatment of PAH.

Related Compounds

Hydroxy Bosentan D4 | Hydroxy Bosentan D6 | Bosentan 13C6 | Bosentan 13C2D4 |

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